Status:

COMPLETED

rTMS in Treatment of Obsessive Compulsive Disorder (OCD)

Lead Sponsor:

Queen's University

Collaborating Sponsors:

Military Medical Academy, Bulgaria

Dokuz Eylul University

Conditions:

Obsessive Compulsive Disorder

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

Low frequency (1Hz) rTMS applied bilaterally and simultaneously over SMA for 6 weeks in addition to the standard treatment regimen for OCD, will lead to significant improvement in patients' symptoms. ...

Eligibility Criteria

Inclusion

  • signed patient informed consent;
  • primary obsessive compulsive disorder;
  • YBOCS score at least 20;
  • males/females 18-65yrs;
  • treated with adequate dose of SSRI at least 8 weeks at some stage of illness;
  • currently using adequate, stable dose of SSRI at least 4 weeks but not responding.

Exclusion

  • schizophrenia, other psychotic disorders, bipolar I, current major depressive disorder (HDRS(17)\>18, substance/alcohol dependence within last 6 months;
  • severe axis II;
  • suicidal score\>=6 on MINI;
  • metallic implant in cranium;
  • severe/unstable medical conditions;
  • not responding to ECT or had TMS in last 6 months;
  • history epilepsy;
  • neurological disorder leading to increased intracranial pressure;
  • severe cardiac disorder/intracardiac lines, pacemakers;

Key Trial Info

Start Date :

January 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 1 2012

Estimated Enrollment :

24 Patients enrolled

Trial Details

Trial ID

NCT00616486

Start Date

January 1 2008

End Date

November 1 2012

Last Update

December 16 2015

Active Locations (3)

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Page 1 of 1 (3 locations)

1

Military Medical Academy

Sofia, Bulgaria

2

Providence Care, Mental Health Services

Kingston, Ontario, Canada, K7L 4X3

3

Dokuz Eylul University

Izmir, Turkey (Türkiye)