Status:
COMPLETED
Intranasal CO2 for Allergic Rhinitis
Lead Sponsor:
University of Chicago
Collaborating Sponsors:
Capnia, Inc.
Conditions:
Allergic Rhinitis
Eligibility:
All Genders
18-45 years
Phase:
NA
Brief Summary
The purpose of this study is to better understand the way in which CO2 (carbon dioxide) affects the symptoms of allergic rhinitis or hayfever. Our intent is to determine if CO2 has an effect on nasal...
Detailed Description
Study design: We performed a randomized, two-way crossover study in subjects with seasonal allergic rhinitis out of season. Subjects came to the Nasal Physiology Laboratory for screening, where they c...
Eligibility Criteria
Inclusion
- Inclusion Criteria
- Males and females between 18 and 45 years of age.
- History of grass and/or ragweed allergic rhinitis.
- Positive skin test to grass and/or ragweed antigen.
- Positive response to screening nasal challenge.
- Exclusion Criteria
- Physical signs or symptoms suggestive of renal, hepatic or cardiovascular disease.
- Pregnant or lactating women.
- Upper respiratory infection within 14 days of study start.
Exclusion
Key Trial Info
Start Date :
February 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2008
Estimated Enrollment :
13 Patients enrolled
Trial Details
Trial ID
NCT00618410
Start Date
February 1 2008
End Date
September 1 2008
Last Update
January 27 2014
Active Locations (1)
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1
University of Chicago
Chicago, Illinois, United States, 60637