Status:

COMPLETED

Home-based vs. Supervised Exercise for People With Claudication

Lead Sponsor:

University of Oklahoma

Collaborating Sponsors:

Oklahoma Center for the Advancement of Science and Technology

National Institute on Aging (NIA)

Conditions:

Intermittent Claudication

Eligibility:

All Genders

35-100 years

Phase:

NA

Brief Summary

The purpose of this study is to examine the effects of a home-based exercise rehabilitation program compared to a supervised exercise program on intermittent claudication (leg pain or discomfort) and ...

Detailed Description

This study seeks to 1) compare the changes in ambulatory function, vascular function, and health-related quality of life in patients limited by intermittent claudication following a home-based exercis...

Eligibility Criteria

Inclusion

  • Positive history of intermittent claudication assessed by the San Diego Claudication Questionnaire
  • Exercise limited by intermittent claudication during a screening treadmill test using the Gardner protocol
  • Ankle/brachial index (ABI) less than 0.90 at rest, which decreases to less than 0.73 immediately following the treadmill exercise test

Exclusion

  • Absence of PAD (peripheral artery disease)
  • Asymptomatic PAD (Fontaine stage I)
  • Rest pain due to PAD (Fontaine stage III)
  • Tissue loss due to PAD (Fontaine stage IV)
  • Medical conditions that are contraindicative for exercise according to the American College of Sports Medicine (e.g., acute myocardial infarction, unstable angina, etc.)
  • Cognitive dysfunction (mini-mental state examination score less than 24)

Key Trial Info

Start Date :

September 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 1 2016

Estimated Enrollment :

135 Patients enrolled

Trial Details

Trial ID

NCT00618670

Start Date

September 1 2006

End Date

September 1 2016

Last Update

April 2 2018

Active Locations (1)

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1

General Clinical Research Center, University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, United States, 73117