Status:
COMPLETED
Pharmacological Intervention in Diabetic Retinopathy
Lead Sponsor:
University of Aarhus
Conditions:
Diabetic Retinopathy
Eligibility:
All Genders
20-35 years
Phase:
NA
Brief Summary
The purpose of this study is to determine if diabetic retinopathy can be treated with prostaglandin analogues, prostaglandin synthesis inhibitors or carbonic anhydrases inhibitors.
Detailed Description
Disturbances in retinal perfusion is believed to be involved in the pathophysiology of diabetic retinopathy. These disturbances may be due to changes in the basal diameter of retinal arterioles and to...
Eligibility Criteria
Inclusion
- Diabetes type 1 with moderate diabetic retinopathy/healthy
- Blood pressure \< 135/85 mmHg
Exclusion
- Eye disease (excluding diabetic retinopathy)
- Allergic
- Kidney disease
- Liver disease
- Severe asthma
- Heart disease
- Hypertension arterial
- Users of drugs that influence the metabolism of the prostaglandins in the carbon dioxide
- Pregnant and breastfeeding women and women who don't use secure contraception
- Persons who can't do without contact lens in the treated eye.
Key Trial Info
Start Date :
September 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2010
Estimated Enrollment :
87 Patients enrolled
Trial Details
Trial ID
NCT00619034
Start Date
September 1 2007
End Date
December 1 2010
Last Update
December 29 2010
Active Locations (1)
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1
Department of Ophthalmology
Aarhus, Denmark, 8000