Status:
COMPLETED
Endothelial Dysfunction and Coronary Artery Spasm
Lead Sponsor:
Kumamoto University
Conditions:
Coronary Vasospasm
Eligibility:
FEMALE
40-90 years
Brief Summary
Non-obstructive coronary artery disease (NOCAD) frequently accounts for myocardial ischemia in women. Endothelial dysfunction is a pathogenic factor in coronary spastic angina (CSA). CSA is an importa...
Detailed Description
Outline of methods: RH-PAT was measured in women with chest pain prior to CAG. Coronary spasm was diagnosed by intra-coronary acetylcholine (ACh) provocation test. Using Flow-Wire, we assessed corona...
Eligibility Criteria
Inclusion
- Stable post-menopausal women complaining angina-like chest pain
Exclusion
- Severe valvular disease
- Hypertrophic cardiomyopathy
- Severe peripheral artery disease
- Uncontrolled hypertension
- Severe collagen diseases
- Acute coronary syndrome
Key Trial Info
Start Date :
August 1 2006
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 1 2009
Estimated Enrollment :
158 Patients enrolled
Trial Details
Trial ID
NCT00619294
Start Date
August 1 2006
End Date
May 1 2009
Last Update
September 26 2013
Active Locations (1)
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1
Kumamoto University Hospital
Kumamoto, Kumamoto, Japan, 860-8556