Status:
COMPLETED
Tocolytic Therapy in Conservative Management of Symptomatic Placenta Previa
Lead Sponsor:
University Hospital, Rouen
Conditions:
Placenta Previa
Eligibility:
FEMALE
18+ years
Phase:
PHASE2
Brief Summary
The objective of our study is to determine the clinical utility related to the maintenance oral nifedipine therapy in patients with symptomatic placenta previa. This study is a prospective, randomized...
Eligibility Criteria
Inclusion
- Placenta previa is diagnosed when the lowest placental edge is located within 5 cm of the internal os at ultrasonography
- Placenta previa may be symptomatic with at least one episode of bleeding
- Estimated gestational age within 24 to 34 weeks
- Maternal age \> 18 years
- Informed consent after received an explanation of the study and an information sheet
- Social affiliation
Exclusion
- Premature rupture of membranes
- Severe bleeding requiring an immediate termination of pregnancy
- Abnormal fetal heart rates requiring an immediate termination of pregnancy
- Intrauterine fetal death
- Pre-eclampsia, chorioamnionitis, liver disease, severe chronic renal disease, heart disease
- Abruptio placentae
- Nifedipine sensibility
- Drugs interaction with nifedipine
Key Trial Info
Start Date :
January 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2012
Estimated Enrollment :
109 Patients enrolled
Trial Details
Trial ID
NCT00620724
Start Date
January 1 2008
End Date
September 1 2012
Last Update
July 10 2014
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University Hospital Rouen
Rouen, France, 76031