Status:
TERMINATED
Comparison of DSCT With IB-IVUS and Angiography in the Assessment of Coronary Artery Disease
Lead Sponsor:
Massachusetts General Hospital
Conditions:
Coronary Artery Disease
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of this study is to compare different methods of looking at atherosclerotic plaques in heart arteries. Identifying the characteristics of these plaques noninvasively would be very valuable...
Detailed Description
The primary objectives of this study are: 1. To compare with contrast angiography, the ability of DSCT to detect and quantify coronary artery stenoses. 2. To compare with gray-scale IVUS, the ability...
Eligibility Criteria
Inclusion
- Males or non-pregnant females
- \> / = 18 years of age
- Scheduled for coronary angiography
Exclusion
- Acute ST-elevation myocardial infarction within last 72 hours
- Current congestive heart failure
- Current cardiogenic shock
- Unstable clinical condition
- Known cardiomyopathy (EF \< 30%)
- Creatinine \>1.5 mg/dL
- Definite allergy to iodinated contrast media
- Current participation in an investigational drug or device research study
- HR \> 65 and contraindications to the administration of beta blockers
- Exclusion criteria assessed during catheterization procedure
- PCI of native coronary vessel not performed
- Left main stenosis \> 50%
- Any vessel contraindicated for IVUS imaging
- Any lesion contraindicated for IVUS imaging
- Inability to pass IVUS catheter
- PCI of bifurcation lesion
Key Trial Info
Start Date :
January 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2009
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT00622167
Start Date
January 1 2008
End Date
June 1 2009
Last Update
February 3 2012
Active Locations (1)
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1
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114