Status:

COMPLETED

Randomized, Controlled Trial of Regular Sildenafil Citrate in the Prevention of Altitude Illness

Lead Sponsor:

Altitude Physiology Expeditions

Collaborating Sponsors:

University of Edinburgh

Conditions:

High Altitude Pulmonary Edema

Acute Mountain Sickness

Eligibility:

All Genders

Phase:

PHASE4

Brief Summary

The purpose of this study is to determine whether regular oral use of sildenafil citrate can prevent or attenuate high altitude illnesses.

Detailed Description

High altitude pulmonary oedema (HAPE) is a life-threatening non-cardiogenic lung injury precipitated by exaggerated pulmonary hypertension. The incidence of this rapidly progressive illness, among the...

Eligibility Criteria

Inclusion

  • Participant in Apex 2 high altitude expedition

Exclusion

  • Previous history of high altitude pulmonary edema

Key Trial Info

Start Date :

March 1 2003

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 1 2008

Estimated Enrollment :

62 Patients enrolled

Trial Details

Trial ID

NCT00627965

Start Date

March 1 2003

End Date

February 1 2008

Last Update

March 4 2008

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