Status:
COMPLETED
An Eval of Neurocognitive Function, Oxidative Damage, and Their Association With Outcomes in METH and Cocaine Abusers.
Lead Sponsor:
University of Cincinnati
Collaborating Sponsors:
National Institute on Drug Abuse (NIDA)
Conditions:
Stimulant Dependence
Eligibility:
All Genders
18-99 years
Brief Summary
The purpose of this study is to determine whether performance on neurocognitive measures predicts treatment outcomes in individuals with substance abuse disorders. A second purpose is to compare the r...
Detailed Description
The primary objective of this study is to replicate the finding that performance on the Stroop color-word interference task is predictive of treatment completion in participants with cocaine use disor...
Eligibility Criteria
Inclusion
- Inclusion Criteria (METH and/or Cocaine Dependent Group):
- be randomized into the CTN-0031 (STAGE-12) trial
- current abuse or dependence for METH and/or cocaine
- endorse METH and/or cocaine as the primary drug of choice
- able to correctly distinguish the colored stimuli on the Stoop task.
- Exclusion Criteria (METH and/or Cocaine Dependent Group):
- history of stroke
- history of a seizure disorder
- Inclusion Criteria (Non-METH and/or Cocaine Dependent Group):
- be 18 years of age or older
- be able to understand the study and provide written informed consent in English
- Exclusion Criteria (Non-METH and/or Cocaine Dependent Group):
- history of stroke
- history of a seizure disorder
- positive urine toxicology screen
- screen positive for Major Depressive Syndrome, other Depressive Syndrome, Panic Syndrome, or other Anxiety Syndrome
- meet criteria for ADHD
- have HIV/AIDS
- history of an injury in which consciousness was lost for more than 30 minutes
- meet DSM-IV criteria for dependence (either current or lifetime) for any psychoactive substance other than nicotine or for abuse (both current and lifetime) for any psychoactive substance other than nicotine or for alcohol for which a life-time history of abuse is allowed
Exclusion
Key Trial Info
Start Date :
February 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 1 2010
Estimated Enrollment :
217 Patients enrolled
Trial Details
Trial ID
NCT00628927
Start Date
February 1 2008
End Date
March 1 2010
Last Update
December 30 2015
Active Locations (6)
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1
Gateway Community Services
Jacksonville, Florida, United States, 32211
2
Maryhaven
Columbus, Ohio, United States, 43207
3
Willamette Family Treatment Services
Eugene, Oregon, United States, 97402
4
ChangePoint, Inc.
Portland, Oregon, United States, 97292