Status:

COMPLETED

An Eight-week Study of Saredutant and Paroxetine as Combination Treatment for Major Depressive Disorder

Lead Sponsor:

Sanofi

Conditions:

Depressive Disorder, Major

Eligibility:

All Genders

18-65 years

Phase:

PHASE3

Brief Summary

The main purpose of this study is to evaluate the efficacy of saredutant 100mg or 30mg once daily in combination with paroxetine 20mg once daily compared to saredutant placebo in combination with paro...

Eligibility Criteria

Inclusion

  • Outpatients with recurrent Major Depressive Disorder

Exclusion

  • Symptoms of current depressive episode for less than 30 days or more than 2 years
  • Mild depression, as measured by standard clinical research scales
  • Significant suicide risk
  • Lack of sexual activity (including masturbation)
  • Other psychiatric conditions that would obscure the results of the study
  • History of failure to respond to antidepressant treatment
  • Pregnancy or breast-feeding

Key Trial Info

Start Date :

February 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 1 2009

Estimated Enrollment :

825 Patients enrolled

Trial Details

Trial ID

NCT00629551

Start Date

February 1 2008

End Date

February 1 2009

Last Update

May 26 2016

Active Locations (8)

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Page 1 of 2 (8 locations)

1

Sanofi-Aventis Administrative Office

Bridgewater, New Jersey, United States, 08807

2

Sanofi-Aventis Administrative Office

Santiago, Chile

3

Sanofi-Aventis Administrative Office

Tallinn, Estonia

4

Sanofi-Aventis Administrative Office

Berlin, Germany

An Eight-week Study of Saredutant and Paroxetine as Combination Treatment for Major Depressive Disorder | DecenTrialz