Status:

COMPLETED

Analysis of Parametrial Lymph Nodes as Sentinel Nodes in Patients With Cervical Cancer

Lead Sponsor:

M.D. Anderson Cancer Center

Conditions:

Cervical Cancer

Eligibility:

FEMALE

Phase:

NA

Brief Summary

The goal of this clinical research study is to find out if the parametrial nodes are "sentinel" nodes (the lymph nodes believed to be the greatest risk for the spread of cancer) and if intraoperative ...

Detailed Description

Lymph nodes are glands that play an important part in your body's defense against infection. They are also the most common site of cancer spread in patients with cervical cancer. Intraoperative lympha...

Eligibility Criteria

Inclusion

  • Patients who are dispositioned to undergo radical hysterectomy or radical trachelectomy and pelvic lymphadenectomy.
  • No evidence of metastases on computed tomography, magnetic resonance imaging, or PET/CT scan.
  • Patients must be good surgical candidates.
  • Patients who have signed an approved informed consent and authorization permitting release of personal health information.
  • For patients of child-bearing age, a negative serum pregnancy test within 72 hours prior to injection of radiocolloid. Child-bearing potential is defined as not post-menopausal for 12 months or no previous surgical sterilization.

Exclusion

  • Patients with known allergies to triphenylmethane compounds or India ink.
  • Patients with a history of retroperitoneal surgery.
  • Patients with a history of pelvic irradiation.
  • Patients who had a cold knife or LEEP cone biopsy within 4 weeks of enrollment.

Key Trial Info

Start Date :

February 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 1 2012

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT00631241

Start Date

February 1 2008

End Date

September 1 2012

Last Update

May 2 2016

Active Locations (1)

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UT MD Anderson Cancer Center

Houston, Texas, United States, 77030