Status:
UNKNOWN
Doxycycline for Lateral Epicondylalgia - RCT
Lead Sponsor:
Kaunas University of Medicine
Collaborating Sponsors:
University Hospital, Linkoeping
Conditions:
Lateral Epicondylalgia (Tennis Elbow)
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
Matrix metalloproteinases are involved in the pathogenesis of tendinopathy. Doxycycline, a widely available pharmaceutical agent mostly used for its antibiotic properties, also functions as an inhibit...
Eligibility Criteria
Inclusion
- Age 18-65
- Pain at the lateral side of the elbow ≥8 weeks
- Local tenderness on palpation of the lateral epicondyle
- Pain on resisted extension of the wrist
Exclusion
- Rheumatic disorder
- History of fibromyalgia or generalised pain
- Elbow surgery (on the painful side)
- Active infection
- Glucocorticoid treatment during the duration of symtoms of epicondylalgia
- NSAID use within 1 w before presentation and during the study
- Pregnancy
- Taking drug that might interact with doxycycline
Key Trial Info
Start Date :
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
34 Patients enrolled
Trial Details
Trial ID
NCT00631501
Last Update
March 7 2008
Active Locations (1)
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1
Dept of Orthopaedics, Kaunas Medical University
Kaunas, Kaunas County, Lithuania