Status:

COMPLETED

Development and Validation of a Symptom Scale for Children With Chronic Graft-versus-Host Disease

Lead Sponsor:

Ann & Robert H Lurie Children's Hospital of Chicago

Collaborating Sponsors:

University of Minnesota

Dana-Farber Cancer Institute

Conditions:

Graft vs Host Disease

Eligibility:

All Genders

5-18 years

Brief Summary

Chronic Graft-versus-Host Disease (cGVHD) is an important cause of morbidity and mortality in patients undergoing allogeneic bone marrow transplantation. cGVHD usually occurs after 100 days following ...

Detailed Description

A large number of children with cGVHD have to deal with many years of a disfiguring and painful chronic illness with the side effects of long term steroid use. The number of stem cell transplants done...

Eligibility Criteria

Inclusion

  • 5-18 years of age
  • Prior allogeneic Stem Cell Transplant, with any graft source, donor type, and GVHD prophylaxis allowed
  • Clinical diagnosis of cGVHD
  • Need for systemic treatment, defined as any medication or intervention delivered
  • No evidence of primary disease relapse
  • Signed, informed consent, and if applicable, adolescent assent

Exclusion

  • Inability to give signed informed consent

Key Trial Info

Start Date :

January 1 2008

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

July 1 2011

Estimated Enrollment :

24 Patients enrolled

Trial Details

Trial ID

NCT00632658

Start Date

January 1 2008

End Date

July 1 2011

Last Update

October 8 2019

Active Locations (1)

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1

Ann & Robert H. Lurie Children's Hospital of Chicago

Chicago, Illinois, United States, 60611