Status:

COMPLETED

Effect of Celecoxib Versus Placebo Before and After Knee Surgery on Overall Use of Analgesics After Surgery

Lead Sponsor:

Pfizer's Upjohn has merged with Mylan to form Viatris Inc.

Conditions:

Arthroscopy

Eligibility:

All Genders

18-65 years

Phase:

PHASE4

Brief Summary

To compare total analgesic use at 24 hours after arthroscopic knee surgery in celecoxib-treated versus placebo-treated patients

Eligibility Criteria

Inclusion

  • Inclusion criteria:
  • Diagnosed (or suspected to have) meniscus trauma of the knee requiring ambulatory arthroscopic knee surgery
  • Willing to participate in study for 36 hours and come to follow-up visit 7 days post surgery

Exclusion

  • Exclusion criteria:
  • Osteoarthritis, inflammatory arthritis, or previous fracture of index joint
  • Received acetaminophen or low dose narcotic (vicodin/tylox) within 8 hours of surgery
  • Have received oral (4 weeks), intramuscular (2 months), intra-articular (3 months) or soft-tissue (2 months) injections of corticosteroids of the first dose of study medication or intra-artcular injections of hyaluronic acid in the index joint within 9 months of the first dose of study medication

Key Trial Info

Start Date :

January 1 2004

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2004

Estimated Enrollment :

204 Patients enrolled

Trial Details

Trial ID

NCT00633438

Start Date

January 1 2004

End Date

June 1 2004

Last Update

February 21 2021

Active Locations (18)

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Page 1 of 5 (18 locations)

1

Pfizer Investigational Site

Phoenix, Arizona, United States, 85023

2

Pfizer Investigational Site

St. Petersburg, Florida, United States, 33713

3

Pfizer Investigational Site

Baltimore, Maryland, United States, 21218

4

Pfizer Investigational Site

Timonium, Maryland, United States, 21093