Status:
COMPLETED
Hereditary Colorectal and Associated Tumor Registry Study
Lead Sponsor:
University of Pittsburgh
Conditions:
Lynch Syndrome
FAP
Eligibility:
All Genders
8-100 years
Brief Summary
After informed consent, participants will be asked to complete a medical/family history questionnaire and provide a blood sample. Participants will also be asked for their permission for study investi...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Identified gene mutation
- Personal history of colorectal cancer diagnosed ≤ 50
- Personal history of cancer with tumor studies suggestive of Lynch syndrome
- Personal history of multiple primary tumors associated with a hereditary cancer syndrome (colorectal, uterus, stomach, ovary, small bowel, hepatobiliary tract, transitional cell carcinoma of the renal pelvis/ureter, brain)
- Personal history of one of the above cancers and a family history of one or more of the above cancers
- Personal or family history of diffuse gastric cancer
- From a known genetic predisposition family
- Personal history of \> 10 colon adenomas (cumulative over a lifetime)
- Personal history of any number of hamartomatous polyps
- Personal history of multiple large (\> 1cm) serrated polyps to right of sigmoid
- Exclusion critera:
- Individuals under the age of 8
- Individuals who cannot travel to Pittsburgh for in-person enrollment
- Individuals who cannot provide informed consent
Exclusion
Key Trial Info
Start Date :
April 1 2012
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 26 2018
Estimated Enrollment :
114 Patients enrolled
Trial Details
Trial ID
NCT00633607
Start Date
April 1 2012
End Date
January 26 2018
Last Update
February 19 2018
Active Locations (1)
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1
University of Pittsburgh
Pittsburgh, Pennsylvania, United States, 15232