Status:

COMPLETED

Effect of Protein-Restricted Diet on Nitrogen Balance and Residual Renal Function in Peritoneal Dialysis (PD) Patients

Lead Sponsor:

Shanghai Jiao Tong University School of Medicine

Conditions:

Chronic Kidney Disease

Peritoneal Dialysis

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

Current therapy recommendations suggest a low protein diet to preserve residual renal function (RRF) before the start of dialysis, but a higher protein intake during dialysis to prevent protein-energy...

Detailed Description

Dietary protein is the major source of nitrogen excreted as urea by the kidney, and a decreased protein intake has been associated with a retardation of kidney function loss in non-dialysis chronic ki...

Eligibility Criteria

Inclusion

  • age 18-80 years
  • stable peritoneal dialysis since at least 1 month
  • with renal function

Exclusion

  • a high probability (assessed by the recruiting physician) of receiving a kidney transplant within one year
  • overt infection within the last month
  • poor compliance in previous dietary prescriptions or irregular check-ups
  • persistent anorexia, vomiting or diarrhea within the last month
  • a CRP of more than 30 mg/dL
  • presence of wasting diseases such as cancer or tuberculosis

Key Trial Info

Start Date :

January 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 1 2008

Estimated Enrollment :

94 Patients enrolled

Trial Details

Trial ID

NCT00633646

Start Date

January 1 2006

End Date

February 1 2008

Last Update

April 28 2008

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