Status:
UNKNOWN
Clinical Study Investigating the Effect of Sodium Nitroprusside Infusion on Thyroidal Function
Lead Sponsor:
Kavaklıdere Umut Hospital
Collaborating Sponsors:
Ankara University
Conditions:
Nitroprusside
Thyroid Hormones
Eligibility:
All Genders
30-85 years
Phase:
PHASE4
Brief Summary
Whether use of SNP during cardiac surgery has any effect on thyroid function has not yet been investigated in humans. The aim of this study was to investigate the effects of SNP administration during ...
Eligibility Criteria
Inclusion
- Patients without history of:
- thyroidal disease
- hypertension
- pulmonary disease
- peripheral vascular disease
- stroke
- recent myocardial infarction within the week prior to operation
- unstable angina pectoris
- liver or kidney dysfunction
- morbid obesity
- cachexia
- sulfonylurea intake
Exclusion
- Patients who needed positive inotropic pharmacologic support during or after the operation
- Patients who developed atrial fibrillation in the post operative period requiring amiodarone therapy
- In addition, patients receiving any medication known to interfere with any step of thyroid hormone metabolism such as
- amiodarone
- propranolol
- furosemide
- non-steroidal anti-inflammatory agents
- steroids
- estrogens
- antacids
- diphenylhydantoin
- spironolactone
Key Trial Info
Start Date :
February 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2008
Estimated Enrollment :
106 Patients enrolled
Trial Details
Trial ID
NCT00636584
Start Date
February 1 2008
End Date
March 1 2008
Last Update
March 14 2008
Active Locations (1)
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1
Kavaklıdere Umut Hastanesi
Ankara, Turkey (Türkiye), 06660