Status:
WITHDRAWN
Corticosteroids Therapy and Pneumocystis Jirovecii Pneumonia (PCP)
Lead Sponsor:
George Washington University
Conditions:
Pneumocystis Carinii Pneumonia
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
To explore the effects of corticosteroid therapy on pulmonary fibrosis and potentially pneumothorax in patients with mild PCP (pO2 \>70mmHg) combined with the standard of care treatment of antibiotic ...
Detailed Description
Although the development of highly active anti-retroviral therapy has substantially reduced the incidence of Pneumocystis jirovecii pneumonia (PCP) among HIV-infected individuals, PCP remains one of t...
Eligibility Criteria
Inclusion
- HIV Infection,
- Hospital admission for suspected PCP,
- Confirmatory test for PCP (bronchoscopy with bronchoalveolar lavage), pO2\>70 mmHg or pO2\<70 mmHg while breathing room air,
- 18 years or older
Exclusion
- Contraindications to corticosteroid therapy,
- Unable and or unwilling to perform PFTS or to return for follow-up evaluations,
- Underlying lung disease such as emphysema, untreated active tuberculosis, Uncontrolled diabetes (fasting glucose \> 250 mg/dL,
- Uncontrolled hypertension (160/95 mmHg),
- Pregnancy
Key Trial Info
Start Date :
February 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2013
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00636935
Start Date
February 1 2008
End Date
August 1 2013
Last Update
June 27 2017
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
George Washington University Medical Faculty Associates
Washington D.C., District of Columbia, United States, 20037