Status:
COMPLETED
The Effect of Allopurinol on Insulin Resistance and Blood Pressure
Lead Sponsor:
Hospital Mateo Orfila
Conditions:
Metabolic Syndrome
Eligibility:
MALE
40-65 years
Phase:
PHASE2
Brief Summary
Studies in animals have found that allopurinol can markedly improve fructose induced metabolic syndrome. In this study we test the hypothesis that allopurinol may lower BP, reduce triglycerides, and i...
Detailed Description
60 male subjects, age 40 to 65 years of age, will be placed on a 3500kcal (55% carbohydrates containing 200 g fructose) for 2 weeks. Half will receive allopurinol mg/day (randomized). At the end of 2 ...
Eligibility Criteria
Inclusion
- Males, age 40 -65 yrs
Exclusion
- None
Key Trial Info
Start Date :
June 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 1 2008
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT00639756
Start Date
June 1 2008
End Date
October 1 2008
Last Update
October 13 2008
Active Locations (1)
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1
Renal Unit, Mateo Orfila Hospital
Menorca, Balearic Islands, Spain, 07703