Status:

COMPLETED

Factorial Study of Metoprolol Succinate TOPROL-XL (324A)

Lead Sponsor:

AstraZeneca

Conditions:

High Blood Pressure (Hypertension).

Eligibility:

All Genders

18-80 years

Phase:

PHASE3

Brief Summary

The purpose of this research study is to determine if treatment with the combination of metoprolol succinate and hydrochlorothiazide is more effective at lowering blood pressure than treatment with ei...

Eligibility Criteria

Inclusion

  • Diastolic blood pressure between 95 and 114 mm at screening and start of treatment

Exclusion

  • Significant conditions which in the opinion of the investigator place the subject at undue risk, eg Renal impairment, hepatitis
  • Known secondary causes of hypertension, eg, Cushing's syndrome, renal artery stenosis, pheochromocytoma, hyperaldosteronism
  • Systolic blood pressure greater or equal to 180 mm Hg at start of trial

Key Trial Info

Start Date :

June 1 2003

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 1 2004

Estimated Enrollment :

1900 Patients enrolled

Trial Details

Trial ID

NCT00642096

Start Date

June 1 2003

End Date

July 1 2004

Last Update

March 25 2009

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