Status:

COMPLETED

New Version Pulmicort Turbuhaler USA Children

Lead Sponsor:

AstraZeneca

Conditions:

Asthma

Eligibility:

All Genders

6-17 years

Phase:

PHASE3

Brief Summary

A comparison of the safety, efficacy and budesonide pharmacokinetics of the currently approved Pulmicort Turbuhaler with a new version of the inhaler, in children and adolescents who have asthma. In a...

Eligibility Criteria

Inclusion

  • Male or females aged 6 to 17 with a diagnosis of asthma for at least 3 months. Have used inhaled corticosteroids for no more than one month before entering the study or none at all.
  • A forced expiratory volume (FEV1) in 1 second of 75% to 90% of predicted normal for those aged 6 to 11 and 60% to 90% for those aged 12 to 17 years.
  • Airway reversibility of at least 12% , use of orally inhaled corticosteroids for no more than one month immediately before entering the study or none at all.

Exclusion

  • Life threatening asthma, Two or more overnight hospitalisations for asthma within 1 year or any emergency room visit for asthma within 6 months of starting study.
  • Use of steroid tablets or injections during the month prior to Visit 1 and use of other asthma medicines (except rescue medication) within 2 weeks prior to the study.
  • Any acute exacerbation of asthma or a respiratory tract infection within 30 days prior to Visit 1. Must not smoke or have smoked.

Key Trial Info

Start Date :

November 1 2002

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2004

Estimated Enrollment :

430 Patients enrolled

Trial Details

Trial ID

NCT00642161

Start Date

November 1 2002

End Date

September 1 2004

Last Update

January 24 2011

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