Status:

COMPLETED

LENS - Long-term Eltrombopag Observational Study

Lead Sponsor:

GlaxoSmithKline

Conditions:

Purpura, Thrombocytopaenic, Idiopathic

Eligibility:

All Genders

Brief Summary

A long term observational ocular safety study in adults who have received study medication (either active drug or placebo) in a phase II or III clinical study evaluating eltrombopag. The study will fo...

Eligibility Criteria

Inclusion

  • Subjects are eligible for enrolment in the study if they have previously participated in an eltrombopag study, either phase II or III, and meet all of the following criteria:
  • Subject has signed and dated a written informed consent for this study.
  • Subject has previously participated in a study evaluating eltrombopag, either phase II or III, and must have received at least one dose of study medication (either active drug or placebo). This excludes subjects from phase I studies (See Section 5.1).
  • The prescribed follow-up ophthalmic assessment at 6 months post end of treatment should be completed as specified in the protocol for the previous study.
  • Subject is able to understand and comply with protocol requirements and instructions.

Exclusion

  • Subjects meeting any of the following criteria must not be enrolled in the study:
  • Subject has received surgery for cataracts and is aphakic or bilaterally pseudophakic.
  • In some countries (i.e. France), a subject is neither affiliated with nor a beneficiary of a social security category.

Key Trial Info

Start Date :

February 1 2007

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

March 1 2013

Estimated Enrollment :

164 Patients enrolled

Trial Details

Trial ID

NCT00643929

Start Date

February 1 2007

End Date

March 1 2013

Last Update

March 23 2017

Active Locations (71)

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Page 1 of 18 (71 locations)

1

GSK Investigational Site

Tucson, Arizona, United States, 85724

2

GSK Investigational Site

Washington D.C., District of Columbia, United States, 20007

3

GSK Investigational Site

Detroit, Michigan, United States, 48202

4

GSK Investigational Site

Durham, North Carolina, United States, 27710