Status:

COMPLETED

A Multicenter, Randomized, Double-Blind, Double-Dummy Comparative Trial of Azithromycin Sustained Release Versus 3-Day Azithromycin for the Treatment of Strep Throat in Adolescents and Adults

Lead Sponsor:

Pfizer

Conditions:

Pharyngitis

Tonsillitis

Eligibility:

All Genders

13+ years

Phase:

PHASE3

Brief Summary

To determine if a single 2.0-g dose of azithromycin SR is at least as effective as a 3-day course of azithromycin (500 mg once daily for 3 days) when used to treat adolescents and adults with strep th...

Eligibility Criteria

Inclusion

  • Patients with evidence of acute group A beta-hemolytic streptococcus (GABHS) pharyngitis/tonsillitis and a positive rapid antigen detection test or positive culture of the pharynx or tonsils for GABHS

Exclusion

  • Patients were excluded if they had treatment with any systemic antibiotic within the previous 7 days, a history of rheumatic fever, a peritonsillar abcess, or were known carriers of GABHS.

Key Trial Info

Start Date :

January 1 2003

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 1 2004

Estimated Enrollment :

598 Patients enrolled

Trial Details

Trial ID

NCT00644293

Start Date

January 1 2003

End Date

April 1 2004

Last Update

June 8 2011

Active Locations (59)

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Page 1 of 15 (59 locations)

1

Pfizer Investigational Site

Clearwater, Florida, United States, 33761

2

Pfizer Investigational Site

Boise, Idaho, United States, 83651

3

Pfizer Investigational Site

Boise, Idaho, United States, 83703

4

Pfizer Investigational Site

Boise, Idaho, United States, 83704