Status:
TERMINATED
Effect of Decreased Pump Prime Volume on Blood Transfusions and Postoperative Complications of Patients Undergoing High Risk Cardiac Surgical Procedures
Lead Sponsor:
University Health Network, Toronto
Conditions:
Cardiac Surgery
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The objective of this study is to evaluate the impact of reduced pump prime on blood transfusions and postoperative complications in patients at high risk of severe hemodilution during CPB. HYPOTHESI...
Eligibility Criteria
Inclusion
- \>18 y of age
- Non-emergent complex cardiac surgery (any procedure other than primary isolated CABG)
- Any of the following: Hb \< 120 g/L (Females) or \< 130 g/L (Males)BSA \< 1.6 m2Creatinine Clearance \< 60 mL/min (Cockcroft Gault Equation)
Exclusion
- aPTT \>50 s, INR\>1.5
- Plt \< 100,000 x 106
- Preoperative Hemodialysis
- Tight aortic stenosis (Aortic Valve Area \< 1 cm2)
- Tight lesion of the left main coronary artery (\> 60%)
- Use of Aprotinin requested by the Surgical Team
Key Trial Info
Start Date :
December 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT00646373
Start Date
December 1 2006
Last Update
April 20 2011
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