Status:

COMPLETED

Investigation of Analgesic and Anti-hyperalgesic Effect of Opioids in Experimental Pain

Lead Sponsor:

University of Aarhus

Conditions:

Pain

Eligibility:

MALE

18-65 years

Phase:

PHASE3

Brief Summary

To compare the analgesic and anti-hyperalgesic effect of Buprenorphine and Fentanyl against experimental pain in skin, muscle and bone. The study will be performed with healthy volunteers.

Eligibility Criteria

Inclusion

  • written informed consent
  • men \> 18 years

Exclusion

  • women
  • known allergy against the investigated drugs
  • ongoing participation in other experiments or participation in other experiments 14 days before screening
  • previously pain or psychiatric conditions
  • simultaneously use of pain killers
  • alcohol
  • previously drug-addict or member of family with drug-addicts
  • chronic constipation
  • ileus
  • inflammatory bowel syndrome
  • abdominal surgery within the last three months

Key Trial Info

Start Date :

February 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2010

Estimated Enrollment :

22 Patients enrolled

Trial Details

Trial ID

NCT00647127

Start Date

February 1 2008

End Date

January 1 2010

Last Update

September 14 2012

Active Locations (1)

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1

Mech Sense, Department of Gastroenterology

Aalborg, Region Nordjyllan, Denmark, 9000