Status:

COMPLETED

Evaluation Of The Efficacy And Safety Of The Doxasozin Gastrointestinal Therapeutic System (GITS) In Patients With Prostate Enlargement

Lead Sponsor:

Pfizer's Upjohn has merged with Mylan to form Viatris Inc.

Conditions:

Prostate

Eligibility:

MALE

50-80 years

Phase:

PHASE4

Brief Summary

The primary objectives were to determine the efficacy and safety of the GITS formulation of Doxazosin in Taiwanese patients with prostate enlargement.

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • Taiwanese male subjects between 50 and 80 years of age who had: a primary diagnosis of BPH, defined as having an enlarged prostate (confirmed by digital rectal examination \[DRE\] and/or B-mode ultrasound); an IPSS score of ≥12; and a Qmax in the range of 5 to 15 mL/sec in a total voided volume of ≥150 mL, were eligible for the study.
  • Exclusion criteria include but not limited to:
  • Previous prostate surgery, presence of a prostate stent or microwave thermotherapy and/or balloon dilatation within the previous 6 months
  • Concomitant therapy or previous therapy within 14 days with agents known to affect bladder or urethral function.

Exclusion

    Key Trial Info

    Start Date :

    November 1 2003

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    January 1 2005

    Estimated Enrollment :

    80 Patients enrolled

    Trial Details

    Trial ID

    NCT00648323

    Start Date

    November 1 2003

    End Date

    January 1 2005

    Last Update

    January 29 2021

    Active Locations (4)

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    Page 1 of 1 (4 locations)

    1

    Pfizer Investigational Site

    Kaohsiung City, Taiwan, 813

    2

    Pfizer Investigational Site

    Taichung, Taiwan

    3

    Pfizer Investigational Site

    Taipei, Taiwan

    4

    Pfizer Investigational Site

    Taoyuan District, Taiwan