Status:
TERMINATED
Effectiveness of Propranolol For Treating People With Post-Traumatic Stress Disorder
Lead Sponsor:
Weill Medical College of Cornell University
Collaborating Sponsors:
National Institute of Mental Health (NIMH)
Conditions:
Post-Traumatic Stress Disorder
Eligibility:
All Genders
18-50 years
Phase:
PHASE4
Brief Summary
This study will evaluate the effectiveness of propranolol in reducing symptoms of distress in people with post-traumatic stress disorder.
Detailed Description
Post-traumatic stress disorder (PTSD) is a common and disabling condition, with about 10% of people having experienced PTSD at some point during their lives. The diagnosis of PTSD requires certain cri...
Eligibility Criteria
Inclusion
- DSM-IV diagnosis of PTSD or meets the five of the six diagnostic criteria for PTSD (event, hyperarousal, re-experiencing, duration, and distress/impaired functioning symptom criteria), but not the avoidance/numbing symptom criteria
Exclusion
- Past or current asthma
- Diabetes or heart disease
- Currently pregnant or breastfeeding
- Concurrent use of daily benzodiazepine; daily use of antidepressant medication allowed if dose has been stable for the 3 months before study entry
- Exposure therapy or additional cognitive therapy during the course of the study (supportive psychotherapy is allowed if ongoing for at least 3 months before study entry)
- Substance abuse
- Current use of beta blockers, amiodarone, chlorpromazine, cimetidine, clonidine, or digoxin
Key Trial Info
Start Date :
December 1 2003
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2009
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT00648375
Start Date
December 1 2003
End Date
September 1 2009
Last Update
January 2 2020
Active Locations (1)
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1
Weill Cornell Medical College
New York, New York, United States, 10065