Status:

COMPLETED

A Study of the Efficacy and Safety of Ziprasidone for the Treatment of Acute Exacerbation of Schizophrenia or Schizoaffective Disorder

Lead Sponsor:

Pfizer's Upjohn has merged with Mylan to form Viatris Inc.

Conditions:

Schizophrenia

Schizoaffective Disorder

Eligibility:

All Genders

18-70 years

Phase:

PHASE4

Brief Summary

This study was conducted to examine the efficacy and tolerability of ziprasidone intramuscular (IM), and to assess the effect of switching from IM to oral ziprasidone for the treatment of acute exacer...

Eligibility Criteria

Inclusion

  • Diagnosis of schizophrenia or schizoaffective disorder.
  • Inpatients with acute exacerbation of psychotic symptoms.
  • Patients with a minimum score of 40 on the BPRS scale (1-7).

Exclusion

  • Concurrent treatment with antipsychotic agents at study drug initiation (within 12 hours prior to study drug initiation); for depot agents a period of two weeks or one cycle, whichever is the longer, must occur between last administration and study drug initiation.
  • Treatment with antidepressants or mood stabilizers within 7 days of start of ziprasidone.
  • Patients currently receiving clozapine.
  • Patients at immediate risk of committing harm to self or others.

Key Trial Info

Start Date :

October 1 2003

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2005

Estimated Enrollment :

28 Patients enrolled

Trial Details

Trial ID

NCT00650429

Start Date

October 1 2003

End Date

May 1 2005

Last Update

February 21 2021

Active Locations (4)

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Page 1 of 1 (4 locations)

1

Pfizer Investigational Site

Monterrey, Nuevo León, Mexico, 64800

2

Pfizer Investigational Site

DF, Mexico, 14420

3

Pfizer Investigational Site

Mexico City, Mexico, 14050

4

Pfizer Investigational Site

Mexico D F, Mexico, 14269