Status:
UNKNOWN
Study of 3-Dimensional Conformal Radiotherapy (3D-CRT) Versus Intensity Modulated Radiotherapy (IMRT) for Head and Neck Squamous Cell Carcinoma (HNSCC)
Lead Sponsor:
Tata Memorial Hospital
Conditions:
Squamous Cell Carcinoma of the Head and Neck
Eligibility:
All Genders
18-65 years
Phase:
PHASE2
Brief Summary
Head \& Neck squamous cell carcinomas are the commonest cancers afflicting the developing countries. Traditionally surgery or radiotherapy alone in the early stages and surgery with postoperative radi...
Detailed Description
1.0 Introduction: Head \& Neck squamous cell carcinomas are the commonest cancers afflicting the developing countries. Traditionally surgery or radiotherapy alone in the early stages and surgery with ...
Eligibility Criteria
Inclusion
- Biopsy proven squamous cell carcinoma of the oropharynx or laryngopharynx.
- AJCC stage T1-3, NO-2b, MO patients with pre-treatment tumor measurements clinically as well as on CT/MRI scans.
- Surgery of the primary tumor limited to excisional or incisional biopsy.
- No form of neck dissection for nodal metastases.
- KPS \> 60 (see appendix I).
- Age \> 18 and \< 65 years.
- No prior history of therapeutic irradiation.
- Patient willing and reliable for follow-up.
- Patient's nutritional \& physical condition compatible with planned therapy.
Exclusion
- Evidence of distant metastases.
- Previous therapeutic irradiation for head \& neck cancer or any other invasive cancer other than squamous or basal cell carcinoma of the skin.
- History of prior malignancy.
- Prophylactic use of amifostine or pilocarpine.
- Active untreated infection like tuberculosis, which preclude the use of systemic chemotherapy or would interfere with completion of treatment.
- Any histopathology other than Squamous Carcinoma.
- Primary nasopharyngeal carcinoma.
- Age \< 18 or \> 65 years.
- Pregnancy or lactating women.
Key Trial Info
Start Date :
August 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2009
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT00652613
Start Date
August 1 2005
End Date
August 1 2009
Last Update
April 11 2008
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Tata Memorial Hospital
Mumbai, Maharashtra, India, 400012