Status:

COMPLETED

Intensity-Modulated Radiation Therapy in Treating Patients With Stage I, Stage II, Stage III, or Stage IV Prostate Cancer

Lead Sponsor:

Mayo Clinic

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Prostate Cancer

Eligibility:

MALE

19+ years

Phase:

PHASE1

PHASE2

Brief Summary

RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Using scintigraphy to plan specialized radiation therapy that delivers a high dose of radiation directly to the tumor may kill...

Detailed Description

OBJECTIVES: * To assess the feasibility of radioimmunoguided intensity-modulated radiotherapy (IMRT) for stage I-IV prostate cancer. * To determine the toxicity and tolerance of this regimen in these...

Eligibility Criteria

Inclusion

  • DISEASE CHARACTERISTICS:
  • Pathologically confirmed prostate cancer
  • Stage I-IV disease (T1-4, N0-1, M0)
  • No evidence of distant metastases (M0) on physical examination or bone scan
  • PATIENT CHARACTERISTICS:
  • ECOG performance status 0-2
  • Hemoglobin ≥ 10.0 g/dL
  • WBC ≥ 3,000/mcL
  • Platelet count ≥ 90,000/mm
  • AST \< 2 times the upper limit of normal
  • No allergy to leuprolide acetate or goserelin
  • PRIOR CONCURRENT THERAPY:
  • Not specified

Exclusion

    Key Trial Info

    Start Date :

    March 1 2002

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    December 1 2007

    Estimated Enrollment :

    100 Patients enrolled

    Trial Details

    Trial ID

    NCT00653757

    Start Date

    March 1 2002

    End Date

    December 1 2007

    Last Update

    March 19 2012

    Active Locations (1)

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    1

    Mayo Clinic in Arizona

    Scottsdale, Arizona, United States