Status:

COMPLETED

Mercury II - Compare the Efficacy and Safety of Lipid Lowering Agents Atorvastatin and Simvastatin With Rosuvastatin in High Risk Subjects With Type IIa and IIb Hypercholesterolemia

Lead Sponsor:

AstraZeneca

Conditions:

Hypercholesterolemia

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

The purpose of this study is to determine whether treatment with rosuvastatin following atorvastatin or simvastatin treatment will improve health outcomes for patients at high risk of Coronary heart d...

Eligibility Criteria

Inclusion

  • Discontinuation of all cholesterol lowing drugs, including dietary supplements.
  • Documented history of, or high risk of coronary heart disease or other established atherosclerotic disease.

Exclusion

  • The use of lipid lowering drugs or dietary supplements after Visit 1.
  • Active arterial disease eg Unstable angina, or recent arterial surgery
  • Uncontrolled hypertension, hypothyroidism, alcohol or drug abuse.
  • Abnormal laboratory parameters as defined in the protocol.

Key Trial Info

Start Date :

November 1 2001

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2004

Estimated Enrollment :

4875 Patients enrolled

Trial Details

Trial ID

NCT00654407

Start Date

November 1 2001

End Date

September 1 2004

Last Update

March 16 2009

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