Status:

COMPLETED

IIIb 6 Week Open Label Multicentre Rosuvastatin & Simvastatin

Lead Sponsor:

AstraZeneca

Conditions:

Fredrickson Type IIa & Type IIb Dyslipidaemia

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

The purpose of this study is to assess the effects on the kidney of rosuvastatin and simvastatin in subjects with Fredrickson Type IIa \& Type IIb Dyslipidaemia

Eligibility Criteria

Inclusion

  • Fasting low density lipoprotein level as defined by the protocol.
  • Fasting triglyceride level as defined by the protocol.

Exclusion

  • The use of lipid lowering drugs or dietary supplements after Visit 1.
  • Active arterial disease eg Unstable angina, or recent arterial surgery
  • Blood creatine levels above the limits defined in the protocol or +4 proteinuria during dietary lead in period.
  • Uncontrolled hypertension, hypothyroidism, alcohol or drug abuse.

Key Trial Info

Start Date :

September 1 2002

Trial Type :

INTERVENTIONAL

End Date :

April 1 2004

Estimated Enrollment :

442 Patients enrolled

Trial Details

Trial ID

NCT00654446

Start Date

September 1 2002

End Date

April 1 2004

Last Update

March 16 2009

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