Status:
COMPLETED
Examining the Long-Term Risks of Oophorectomy
Lead Sponsor:
Parker, William H., M.D.
Collaborating Sponsors:
Ethicon, Inc.
Conditions:
Coronary Heart Disease
Stroke
Eligibility:
FEMALE
30-55 years
Brief Summary
At the time of hysterectomy for benign disease, the overall health benefits of preserving ovarian function in a large population of women have not been established.
Detailed Description
We are conducting a prospective, observational study of 32,175 women participants of the Nurse's Health Study who had a hysterectomy with or without removal of both ovaries. We are evaluating mortalit...
Eligibility Criteria
Inclusion
- Women who had hysterectomies were classified into simple hysterectomy or hysterectomy with both ovaries removed.
Exclusion
- Evidence of cancer, coronary heart disease (MI or Angina Pectoris), stroke, or hip fracture before entering the study were excluded. Cancer as an indication for hysterectomy also excluded.
- Women reporting unilateral oophorectomy, unknown oophorectomy status, unknown age of hysterectomy, or those who had oophorectomy before hysterectomy were excluded.
Key Trial Info
Start Date :
January 1 1980
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 1 2004
Estimated Enrollment :
32175 Patients enrolled
Trial Details
Trial ID
NCT00655447
Start Date
January 1 1980
End Date
June 1 2004
Last Update
April 9 2008
Active Locations (1)
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1
Parker, Rosenman, Rodi Gynecology Group
Santa Monica, California, United States, 90401