Status:
COMPLETED
Ethnic Differences in Response to Topical Capsaicin: A Psychophysical Study on Healthy Subjects
Lead Sponsor:
Wake Forest University
Conditions:
Healthy
Eligibility:
All Genders
18-50 years
Phase:
PHASE4
Brief Summary
The purpose of this research is to study how people respond differently to capsaicin in different racial groups and the effect it has on your pain levels. Capsaicin is a natural product made from hot ...
Detailed Description
To comprehensively evaluate the ethnic differences in response to topical capsaicin and its effect on thermal sensory thresholds.
Eligibility Criteria
Inclusion
- Adult men and women who are between 18 and 50 years of age.
- Subjects must be in general good health with no skin disease, disease state or physical condition which would impair evaluation of pain perception or which would increase their health risk by study participation as determined by the investigators.
- Women of childbearing potential will be required to have a negative pregnancy test in order to enroll in the study.
Exclusion
- Adults over age 50.
- Children less than 18 years of age.
- Unable to complete the required measures.
- Diagnosis of diseases that would affect the measurement of pain perception.
- Currently enrolled in any investigational study in which the subject is receiving any type of drug, biologic, or non-drug therapy and subjects undergoing treatment with another investigational drug or approved therapy for investigational use within 30 days prior to study participation.
- Use of oral analgesic or other medications known to interfere with pain perception in the week prior to the study.
- Use of emollient on the forearms on the day of the study visit.
- Use of medicated topical preparations on the forearms for the week prior to the study.
- Known history of neuropathy causing diseases such as uremia.
- Known history of uncontrolled thyroid disease.
- Known history of diabetes mellitus.
- Allergy to capsaicin.
- Pregnant women.
Key Trial Info
Start Date :
February 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2009
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT00655811
Start Date
February 1 2008
End Date
October 1 2009
Last Update
September 10 2018
Active Locations (1)
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1
Wake Forest University Health Sciences Dermatology
Winston-Salem, North Carolina, United States, 27157