Status:
COMPLETED
Treatmant of Oral Lichen Planus With Lycopene
Lead Sponsor:
College of Dental Sciences, India
Conditions:
Lichen Planus, Oral
Eligibility:
All Genders
Phase:
PHASE2
Brief Summary
the purpose of this study was to evaluate that if lycopene, a potent antioxidant can be used in the treatment of oral lichen planus. this could be useful as lycopene has no reported side effects and h...
Detailed Description
Lichen planus, a chronic inflammatory mucocutaneous disease, occurs in about 2% of the adult population, affecting the skin and or oral mucosa. Clinically, lichen planus appears in keratotic, atrophic...
Eligibility Criteria
Inclusion
- Patients who were physically healthy and well oriented in time space and as a person.
- Patients clinically \& histopathologically diagnosed to be suffering from oral lichen planus.
- Patients who had symptoms i.e. pain and/or burning sensation secondary to oral lichen planus.
- Patients not on any treatment for the same. In case they were, then such treatment was stopped and a washout period of two weeks was given.
- Patients who agreed to take medication supplied.
- Patients who were willing for evaluation once in every two weeks for 8 weeks and also agreed to follow up every 30 days for 60 days.
- Patients who agreed for the biopsy and hematological examination.
Exclusion
- Patients suffering from any systemic disease/s like Diabetes, Hypertension, Cardiovascular system disease, Renal dysfunction, Liver disorders etc.
- Patients with any other mucosal disease or any other skin disease which may be associated with oral lesions.
- Patients on any drug therapy which may cause lichen planus like lesions.
- Patients with findings of any physical or mental abnormality, which would interfere with or be affected by the study procedure.
- Patients with a known allergy or contraindication to study medications.
Key Trial Info
Start Date :
December 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2006
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT00656214
Start Date
December 1 2004
End Date
July 1 2006
Last Update
April 10 2008
Active Locations (1)
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1
Department of oral medicine & radiology, College of dental sciences
Davangere, Karnataka, India, 577004