Status:
COMPLETED
Identification of Criteria of the Success of the Endarterectomy in Chronic Pulmonary Post Embolic Hypertension
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Conditions:
Chronic Thromboembolic Pulmonary Hypertension
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
In order to improve effectiveness of the surgical operation thanks to a reduction in the rate of failure, this study will allow us to identify predictive angiographic and CT finding of surgical failur...
Detailed Description
Chronic thromboembolic pulmonary hypertension(CTEPH) is caused by obstruction of the large pulmonary arteries by acute and recurrent pulmonary emboli, and organization of these blood clots. ANTOINE BE...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Patients addressed to the reference centre of pulmonary hypertension for a suspected CPC-PE
- Achieving an assessment prior to the operation, including:1) Right cardiac catheterization confirming HTP with a mean pulmonary arterial pressure\> 25 mm Hg at rest; 2) Echography and Doppler of the lower limbs in search of phlebitis sequela; 3) Pulmonary scintigraphy with 6 views in ventilation and perfusion; 4) Digital pulmonary angiography; 5) A 64 detector pulmonary computed tomography; 6) Having read the briefing note and given their agreement.
- Exclusion criteria:
- Refusal examinations .
- Patient for which one method is contraindicated
- Patient considered not operable by the staff
- Life expectancy of less than 3 months
- Geographical distance for the clinical follow-up at 3 months
- Renal insufficiency (creatinine clearance \<30 mL / min)
- Proven allergy to iodinated contrast agents
- Pregnant woman.
Exclusion
Key Trial Info
Start Date :
January 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2011
Estimated Enrollment :
249 Patients enrolled
Trial Details
Trial ID
NCT00657722
Start Date
January 1 2008
End Date
November 1 2011
Last Update
April 11 2013
Active Locations (2)
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1
Hôpital Antoine Beclere
Clamart, France, 92141
2
Hospital Marie Lannelongue
Le Plessis-Robinson, France, 92350