Status:
COMPLETED
Bisphosphonates and Impaction Grafting in Hip Revision
Lead Sponsor:
Region Skane
Conditions:
Aseptic Loosening of the Hip Prosthesis
Eligibility:
All Genders
45-80 years
Phase:
PHASE2
Brief Summary
The primary focus of this study is to investigate whether increased bone density of the graft in revision arthroplasty of the hip can cause a decreased micromotion of the implant relative to the femur...
Detailed Description
Morsellized compacted bone allograft can be used for revision arthroplasty of the hip. Treating the graft locally with an antiresorptive substance such as a bisphosphonate has decreased the graft reso...
Eligibility Criteria
Inclusion
- Patients with aseptic loosening and osteolysis scheduled for hip revision using allograft and impaction technique
- Obtained informed consent
- Pregnancy excluded in women of childbearing age
Exclusion
- Patients with known renal disease or S-creatinine \>175 mcmol/L
- Patients with S-calcium 2.75 mmol/L
- Patients with diagnosed Rheumatoid arthritis
- Patients with active primary hyperparathyroidism
Key Trial Info
Start Date :
March 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2017
Estimated Enrollment :
32 Patients enrolled
Trial Details
Trial ID
NCT00658268
Start Date
March 1 2008
End Date
August 1 2017
Last Update
August 15 2017
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Lund University Hospital
Lund, Sweden, SE-22185