Status:
COMPLETED
Effects of Mild Hypobaric Hypoxia on Oxygen Saturation During Sleep
Lead Sponsor:
The Boeing Company
Collaborating Sponsors:
Simon Fraser University
Massey University
Conditions:
Sleep-related Respiratory Disturbance
Eligibility:
MALE
30-60 years
Phase:
NA
Brief Summary
Ascent to altitude lowers oxygen saturation. In addition, sleep lowers oxygen saturation at any altitude. In a prior study, we observed that sleep at 8000 feet resulted in pronounced reduction in oxyg...
Detailed Description
This study has 6 primary objectives/hypotheses: 1. Replicate findings of earlier study in which no effects of altitude were observed on post sleep neurobehavioral performance, sleep quantity or quali...
Eligibility Criteria
Inclusion
- Male
- Between 30 and 60 years of age.
- Healthy, able to pass FAA Class III examination
- Body mass index less than 30
- Height less than 75 inches
- Ability to read and speak English
Exclusion
- Prolonged residence above 5000 feet
- Recent travel to altitudes above 5000 feet
- Use of drugs or medications that affect sleep
- History of mood or psychiatric disorders that affect sleep.
- History of medical conditions that increase risk of adverse effects of hypoxia.
- Apnea hypopnea index greater than 15/hr at ground level.
Key Trial Info
Start Date :
May 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2009
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT00659009
Start Date
May 1 2008
End Date
March 1 2009
Last Update
August 15 2012
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Environmental Physiology Unit, School of Kinesiology, Simon Fraser University
Burnaby, British Columbia, Canada, V5A 1S6