Status:

COMPLETED

Antibiotic Study for Dental Implants

Lead Sponsor:

OraPharma

Conditions:

Periodontitis

Eligibility:

All Genders

21+ years

Phase:

PHASE3

Brief Summary

This study is for people at least 21 years old who have signs of problems, like swollen gums and shrinking bones, by dental implants.

Detailed Description

At Visit 1, the dentist will: * do an oral exam * ask some questions * decide if the person qualifies for being in the study * make an appointment for Visit 2 if they qualify At Visit 2 (Baseline), ...

Eligibility Criteria

Inclusion

  • 21 years of age and good general health
  • appropriately documented Informed Consent
  • willing to adhere to the study schedule, prohibitions and restrictions specified in the protocol
  • female subjects must meet the pregnancy and contraceptive requirements
  • must have oral health appropriate for study inclusion

Exclusion

  • oral health inappropriate for study inclusion
  • females self-reporting pregnancy or lactation, or having a positive urine pregnancy result
  • reporting any of the following conditions:
  • allergy to a tetracycline-class drug
  • systemic medical conditions requiring antibiotic prophylaxis prior to invasive dental procedures
  • active systemic infectious disease such as hepatitis, human immunodeficiency virus (HIV) or tuberculosis
  • diagnosed with clinically significant or unstable organic disease, or compromised healing potential, heart murmurs, histories of rheumatic fever, valvular disease or prosthetic joint replacement
  • participation in a dental clinical trial or use of an investigational drug within 30 days of enrollment
  • employees of the Investigator or study center, with direct involvement in the proposed study or other studies, as well as family members of the employees or the Investigator
  • anyone who the investigator determines should not be included in the study for any reason that could compromise safety or the analysis of study results

Key Trial Info

Start Date :

April 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 1 2009

Estimated Enrollment :

44 Patients enrolled

Trial Details

Trial ID

NCT00662532

Start Date

April 1 2008

End Date

April 1 2009

Last Update

December 12 2011

Active Locations (4)

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Page 1 of 1 (4 locations)

1

JJCPPW Investigational Site

Aurora, Colorado, United States, 80012

2

JJCPPW Investigational Site

Ann Arbor, Michigan, United States, 48106

3

JJCPPW Investigational Site

Hazlet, New Jersey, United States, 07730

4

JJCPPW Investigational Site

Seattle, Washington, United States, 98195