Status:
COMPLETED
Effects of Spironolactone on Matrix Metalloproteinases (MMPs) in Heart Failure
Lead Sponsor:
Tottori University Hospital
Conditions:
Chronic Stable Heart Failure
Eligibility:
All Genders
Phase:
PHASE4
Brief Summary
The purpose of this study is to evaluate the effects of spironolactone on circulating MMP levels and insulin resistance in patients with chronic heart failure.
Detailed Description
Myocardial fibrosis is observed in failing hearts. MMPs are considered markers of fibrosis. Recently, circulating MMPs can be measured and are elevated in patients with chronic heart failure (CHF). It...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- chronic stable heart failure
Exclusion
Key Trial Info
Start Date :
January 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2005
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT00663195
Start Date
January 1 2004
End Date
December 1 2005
Last Update
April 22 2008
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