Status:

COMPLETED

Facial Expression Recognition of Emotion and Categorization of Emotional Words in Parkinson's Disease. Impact of L-Dopa and Deep Brain Stimulation of Subthalamic Nucleus

Lead Sponsor:

University Hospital, Clermont-Ferrand

Conditions:

Idiopathic Parkinson's Disease

Eligibility:

All Genders

30-75 years

Phase:

NA

Brief Summary

Parkinson'disease is a neurodegenerative disorder characterised by bradykinesia, rigidity, rest tremor and postural instability. Dopaminergic therapy such as L-Dopa and dopamine agonists usually leads...

Detailed Description

40 patients with an Idiopathic Parkinson's disease divided in two groups : * 20 patients evaluated before surgery and 6 month after surgery * 20 patients only evaluated after surgery. 40 paired he...

Eligibility Criteria

Inclusion

  • Age : 30-75 years
  • Patient with an idiopathic Parkinson's disease according to the criteria of the "Parkinson's Disease Society Brain Bank" (Hughes et al., 1992)
  • Patient treated with a deep brain stimulation according to the French consensus conference of treatment of Parkinson's disease (Consensus Conference Proceeding, 2000)
  • Effect of the stimulation 50%
  • Affiliation to social security
  • Agreement of patients

Exclusion

  • Patients suffering of an atypical Parkinson syndrome
  • Patients with severe tremor before surgery
  • Patients with a vision contrast altered.
  • Patients who do not understand the words associated with an emotion
  • Pregnant women
  • Person who participate to an other study

Key Trial Info

Start Date :

September 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 1 2009

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT00664157

Start Date

September 1 2007

End Date

October 1 2009

Last Update

January 19 2011

Active Locations (1)

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1

CHU

Clermont-Ferrand, France, 63003