Status:

COMPLETED

Comparison Study Between Protopic (Tacrolimus Ointment) and Elidel (Pimecrolimus Cream) in Pediatric Patients With Mild Atopic Dermatitis

Lead Sponsor:

Astellas Pharma Inc

Conditions:

Dermatitis, Atopic

Eligibility:

All Genders

2-16 years

Phase:

PHASE4

Brief Summary

A study to compare the safety and efficacy of Protopic and Elidel in treating mild Atopic Dermatitis in pediatric patients

Eligibility Criteria

Inclusion

  • Patient has a diagnosis of Atopic Dermatitis rated mild using the Investigator's Global Atopic Dermatitis Assessment involving a minimum of 5% of the body surface area, and the maximum of 20% of the body surface area
  • If female, and of childbearing potential, patient has a negative pregnancy test and agrees to practice effective birth control during the study

Exclusion

  • Patient has a skin disorder other than Atopic Dermatitis in the areas to be treated
  • Patient has extensive scarring or pigmented lesions in the areas to be treated that would interfere with rating of efficacy parameters
  • Patient has clinically infected Atopic Dermatitis at baseline
  • Patient is likely to require systemic corticosteroids, or the patient is likely to require intranasal or inhaled corticosteroids for an off-label indication or at higher doses than the maximum labeled dosing for the drug
  • Patient has a known hypersensitivity to macrolides or any excipient of either study medication
  • Patient has a chronic condition which is either not stable or not well controlled
  • Patient is pregnant or breast feeding an infant

Key Trial Info

Start Date :

December 1 2002

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 1 2003

Estimated Enrollment :

426 Patients enrolled

Trial Details

Trial ID

NCT00667160

Start Date

December 1 2002

End Date

November 1 2003

Last Update

September 18 2014

Active Locations (19)

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Page 1 of 5 (19 locations)

1

San Diego, California, United States, 92123

2

New Haven, Connecticut, United States, 06519

3

Miami, Florida, United States, 33136

4

Miami, Florida, United States, 33155