Status:
COMPLETED
Primary Pigmented Nodular Adrenocortical Disease (PPNAD) and the CARNEY Complex (CNC)
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Collaborating Sponsors:
URC-CIC Paris Descartes Necker Cochin
Conditions:
Primary; Complex
Pigmented Nodular Adrenocortical Disease, Primary, 1
Eligibility:
All Genders
Brief Summary
Cohort CNC-PPNAD will be investigated with clinical, genetic, biological and imaging work-up every year during 3 years. Cohort L-MC will be investigated clinically at inclusion and a PERKAR1A genotype...
Detailed Description
The primary aim is to assess the clinical manifestations of the CARNEY Complex (CNC) and/or the primary pigmented nodular adrenocortical disease (PPNAD) in patients with CNC, isolated PPNAD or carrier...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- CNC group :
- patient with the CARNEY complex (CNC) or the primary pigmented nodular adrenocortical disease (PPNAD) or a germinal mutation of the gene of CARNEY Complex or PPNAD.
- No age criteria
- Inform consent of the patient or the parental authority collected
- Realization of a preliminary medical examination
- Affiliated with a social security system ( profit or having right)
- MC-L group :
- Patient with periorificial lentiginosis or cardiac myxoma
- or previous history of periorificial lentiginosis or cardiac myxoma
- age \> or = 18 years old
- Realization of a preliminary medical examination
- Affiliated with a social security system ( profit or having right)
- Exclusion criteria :
- CNC group and MC-L group:
- refusal or incapacity to take part in the study
Exclusion
Key Trial Info
Start Date :
January 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 1 2016
Estimated Enrollment :
133 Patients enrolled
Trial Details
Trial ID
NCT00668291
Start Date
January 1 2008
End Date
January 1 2016
Last Update
November 20 2025
Active Locations (1)
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1
Hôpital Cochin
Paris, France, 75679