Status:

COMPLETED

Effect of Dietary Polyphenols on Insulin Sensitivity

Lead Sponsor:

United States Department of Agriculture (USDA)

Conditions:

Insulin Resistance

Eligibility:

All Genders

25-65 years

Phase:

PHASE1

Brief Summary

A large and growing segment of the population is prediabetic. Dietary interventions that improve insulin sensitivity may be important in preventing the progression to full-blown diabetes in these indi...

Detailed Description

How does the amount consumed of cocoa and tea polyphenols (flavon-3-ol monomers and oligomers) affect insulin sensitivity in insulin resistant individuals?

Eligibility Criteria

Inclusion

  • Individuals who are insulin resistant based on routine clinical measurements (Stern et al., 2005).

Exclusion

  • BMI \< 27 kg/m²
  • Age \< 25 and \> 65 years
  • Pregnant women or women who plan on becoming pregnant during the study
  • Postpartum women
  • Lactating women
  • Diabetes mellitus
  • Kidney disease
  • Liver disease
  • Certain cancers
  • Smokers

Key Trial Info

Start Date :

January 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2007

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT00668928

Start Date

January 1 2006

End Date

December 1 2007

Last Update

April 29 2008

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