Status:

COMPLETED

Examination of Quantitative Electroencephalographic (QEEG) Biomarkers in Huntington's Disease

Lead Sponsor:

University of California, Los Angeles

Collaborating Sponsors:

High Q Foundation

Conditions:

Huntington's Disease

Eligibility:

All Genders

21-85 years

Brief Summary

The pace of basic science research defining the mechanisms of selective neuronal degeneration in Huntington disease (HD) has far exceeded the pace of translation of this information into clinically ef...

Detailed Description

We will examine three subject groups in this study: those with mild HD, those with moderate HD, and normal controls. Fifteen subjects will be examined in each group, for an overall total of forty-five...

Eligibility Criteria

Inclusion

  • Inclusion criteria:
  • Subjects affected by HD or those who are at risk for HD by virtue of having a first-degree relative with the illness, methamphetamine abuse or dependence, as well as normal controls, can participate.
  • All subjects will be above the age of 21.
  • Subjects will be recruited from clinical settings, and will also be self-referred.
  • Exclusion criteria:
  • Individuals with pacemakers, infusion pumps, or metallic shrapnel will be excluded from MRI assessments.
  • Such implanted metals may be attracted by the MRI machine and put the individual at risk.
  • Moreover, individuals with a history of brain surgery and/or skull fracture will also be excluded.

Exclusion

    Key Trial Info

    Start Date :

    September 1 2006

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    February 1 2008

    Estimated Enrollment :

    42 Patients enrolled

    Trial Details

    Trial ID

    NCT00670709

    Start Date

    September 1 2006

    End Date

    February 1 2008

    Last Update

    November 9 2023

    Active Locations (1)

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    UCLA Laboratory of Brain, Behavior,a nd PHarmacology

    Los Angeles, California, United States, 90024