Status:
COMPLETED
Effects of Low-Dose Theophylline During Chronic Obstructive Pulmonary Disease (COPD) Exacerbations
Lead Sponsor:
Hospital Universitari Son Dureta
Collaborating Sponsors:
Fondo de Investigación Sanitaria (FIS)
Sociedad Española de Neumología y Cirugía Torácica
Conditions:
COPD
Eligibility:
MALE
40-75 years
Phase:
NA
Brief Summary
Molecular mechanisms of COPD exacerbations and the modulating effect of low dose theophylline on that inflammation are elucidated in this project. NF-kappa B-dependent pathway and acetylation status o...
Eligibility Criteria
Inclusion
- Severe COPD according to GOLD guidelines
- Age between 40 and 75
- Admission to hospital due to COPD exacerbation
Exclusion
- History of asthma
- Pulmonary embolism
- Pneumonia
- Other chronic inflammatory disease
- Patient on theophylline at the time of admission
- Patient on oral steroids at the time of admission
Key Trial Info
Start Date :
June 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2007
Estimated Enrollment :
35 Patients enrolled
Trial Details
Trial ID
NCT00671151
Start Date
June 1 2005
End Date
December 1 2007
Last Update
May 5 2008
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Hospital Universitario Son Dureta
Palma de Mallorca, Balearic Islands, Spain, 07014