Status:
COMPLETED
Study of Pain Processing in Subjects Suffering From Obstructive Sleep Apnea
Lead Sponsor:
Stanford University
Conditions:
Sleep Apnea, Obstructive
Eligibility:
MALE
18-55 years
Brief Summary
We would like to test the effect of opioid medication on pain sensitivity in subjects who have been diagnosed with a sleep disorder called Obstructive Sleep Apnea (OSA) compared to other subjects with...
Detailed Description
The purpose of the study is to test the hypothesis that patients who suffer from moderate-to-severe OSA have increased pain thresholds and are more sensitive to the analgesic effects of opioids compar...
Eligibility Criteria
Inclusion
- Male 2 .18 - 55 years of age 3. Body mass index (BMI) lower or equal to 30 kg/m2 4. Absence of severe systemic disease that results in functional limitations (i.e. poorly controlled hypertension, angina pectoris, prior myocardial infarction, pulmonary disease that limits activity) 5.Subjects must be able to comprehend spoken and written English
Exclusion
- Major psychiatric, neurological, or neuromuscular disorder 2. Known diabetes mellitus or thyroid disease 3. Allergy to study medication (remifentanil) 4. History of addiction 5. Alcohol consumption which exceeds 2 drinks per day and /or drug abuse. 6. Chronic or acute use of opioids, or other medications affecting the CNS.
Key Trial Info
Start Date :
February 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
August 1 2010
Estimated Enrollment :
56 Patients enrolled
Trial Details
Trial ID
NCT00672737
Start Date
February 1 2008
End Date
August 1 2010
Last Update
August 7 2017
Active Locations (1)
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1
Stanford University School of Medicine
Stanford, California, United States, 94305