Status:
COMPLETED
Assessment of Mechanisms of Improved Wound Healing
Lead Sponsor:
The University of Texas Medical Branch, Galveston
Collaborating Sponsors:
National Institute of General Medical Sciences (NIGMS)
Conditions:
Burns
Eligibility:
All Genders
Up to 90 years
Phase:
PHASE2
PHASE3
Brief Summary
The purpose of this study is to find ways to improve wound healing and decrease the negative effects of trauma from burn injury.
Detailed Description
This study involves research and the investigators hope to learn the following: how or what effect one or more anabolic ("tissue building") agents have on muscle metabolism, wound healing, and immune ...
Eligibility Criteria
Inclusion
- Patient is between 0 and 90 years of age
- Patient 18 years and older consents to participate in study protocol. If patient is not able to consent, consent will be obtained from closest family member or legal guardian. Parental permission will be obtained for patients less than 18 years of age. Assent will be obtained from children 7-17 years of age if child is physically/mentally able to do so.
- greater than 30% TBSA burn requiring at least 1 operation with donor sites for skin grafting
Exclusion
- Known history of AIDS, AIDS-related complex, Human Immunodeficiency Virus
- History of cancer within 5 years
- Tuberculosis, arthritis, cirrhosis, hyperlipidemia, bone or endocrine diseases, autoimmune diseases
- Chronic glucocorticoid or non-steroidal anti-inflammatory drug therapy
Key Trial Info
Start Date :
July 1 2000
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2013
Estimated Enrollment :
644 Patients enrolled
Trial Details
Trial ID
NCT00673309
Start Date
July 1 2000
End Date
April 1 2013
Last Update
July 3 2023
Active Locations (1)
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1
University of Texas Medical Branch
Galveston, Texas, United States, 77550