Status:

COMPLETED

Corneal Collagen Cross-Linking for Ectasia (CXL)

Lead Sponsor:

Glaukos Corporation

Conditions:

Ectasia

Eligibility:

All Genders

14+ years

Phase:

PHASE3

Brief Summary

Prospective, randomized multicenter study to determine the safety and effectiveness of performing corneal collagen cross-linking (CXL) using riboflavin and UVA light in eyes with ectasia after refract...

Detailed Description

Subjects are randomized to a control group or a treatment group, with the control group crossed over to the treatment group at the 3 month visit. Corneal collagen cross-linking is performed as a singl...

Eligibility Criteria

Inclusion

  • Diagnosis of ectasia after refractive surgery
  • Documented ectasia on Pentacam or topography map
  • BSCVA worse than 20/20
  • Must complete all study visits

Exclusion

  • History of delayed wound healing
  • History of corneal melt or corneal dystrophy

Key Trial Info

Start Date :

December 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 1 2011

Estimated Enrollment :

130 Patients enrolled

Trial Details

Trial ID

NCT00674661

Start Date

December 1 2007

End Date

November 1 2011

Last Update

April 26 2021

Active Locations (10)

Enter a location and click search to find clinical trials sorted by distance.

Page 1 of 3 (10 locations)

1

Shiley Eye Center

La Jolla, California, United States, 92093

2

Gordon -Weiss Vision Institute

San Diego, California, United States, 91222

3

Center for Excellence in Eye Care

Miami, Florida, United States, 33176

4

Price Vision Group

Indianapolis, Indiana, United States, 46260