Status:

COMPLETED

Antenatal Corticoid Therapy for Late Preterm Babies

Lead Sponsor:

Instituto Materno Infantil Prof. Fernando Figueira

Conditions:

Hyaline Membrane Disease

Transient Tachypnea

Eligibility:

FEMALE

18-49 years

Phase:

NA

Brief Summary

This study aims to determine the effectiveness of antenatal corticosteroid therapy in late preterm babies. The investigators hypothesis is corticoid accelerates fetal lung maturation even after 34 wee...

Detailed Description

Late preterm babies have important morbidity when compared with term babies, with oxygen requirement and more days of hospitalization. If antenatal corticosteroid therapy is necessary for fetal lung m...

Eligibility Criteria

Inclusion

  • Pregnancy between 34 and 36 weeks
  • Confirmed gestational age (LMP, USG)
  • Alive fetus
  • Imminent risk of preterm delivery

Exclusion

  • Multiple pregnancy
  • Major fetal malformations
  • Comproved fetal lung maturity
  • Maternal or fetal indication for immediate interruption of pregnancy
  • Maternal hemorrhagic syndromes (placenta previa, abruptio placenta)
  • Chorioamnionitis
  • Chronic use of corticosteroids
  • Previous use of corticosteroids for fetal lung maturation in the current pregnancy

Key Trial Info

Start Date :

May 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 1 2010

Estimated Enrollment :

320 Patients enrolled

Trial Details

Trial ID

NCT00675246

Start Date

May 1 2008

End Date

May 1 2010

Last Update

June 9 2010

Active Locations (1)

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Instituto Materno Infantil Prof. Fernando Figueira

Recife, Pernambuco, Brazil, 50070550